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This paper inaugurates a reflection on what it would imply to think about care in the context of the ecosocial crises that afflict the planet today. Transdisciplinary studies on the anthropocene have modified the epistemic criteria for thinking about our worlds. Drawing on a particular conceptualization of the Anthropocene in relation to health, this article reflects on the construction of diagnosis and on the need for a pluralization of therapeutic approaches and care practices. Thus, a conceptualization of the anthropocene in some of its implications for health is presented. In a second moment, weaving from Latin American social medicine, this text links sociocultural epidemiology, collective health and anthropocene studies.